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Therano’s blood take a look at accuracy on the coronary heart of Elizabeth Holmes’ prison trial

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Therano’s blood take a look at accuracy on the coronary heart of Elizabeth Holmes’ prison trial

Former Theranos CEO Elizabeth Holmes will attend the US government fraud court hearing against her on May 5, 2021.

CNBC

Former Theranos CEO Elizabeth Holmes promised a technological breakthrough, but it really was a house of cards, prosecutors said during a trial Wednesday.

“Miss Holmes went out, told the world, and told investors, we have tests with the highest accuracy rate,” said US assistant attorney Robert Leach, adding that her expert’s testimony “lies.”

The argument was in response to efforts by the defense, Dr. Stephen Master, an associate professor of pathology and laboratory in the University of Pennsylvania Medical School, from taking a stand. In 2013, after interviewing Holmes at a conference, Master said that her claims about Theranos’ miniLab technology “fell far short of previous claims”.

Holmes’ defenders argued that the master was used as a “parrot” by the government and that his conclusions about certain Theranos blood tests were “based on emails and customer complaints,” not practical experience.

Wednesday’s hearing was the second day of the argument about what evidence can be admitted and excluded from Holmes’ criminal fraud trial, which begins August 31st.

Prosecutors, among other things, alleged that Holmes was presenting an inappropriate defense in good faith.

“Efforts to return money to victims cannot undo the fraud once it is committed,” said John Bostick, another US assistant attorney.

The judge is expected to rule on critical motions, including whether to provide evidence of Holmes’ assets and expenses, private text exchanges and regulatory reports by the end of the week.

The hearing came when a former Theranos executive who had been close to Holmes in the company’s final days told CNBC that management was discussing Holmes’ resignation as CEO on several occasions. For Holmes, however, “that was a non-runner”.

“If she had resigned, I think she would have saved herself a lot of legal danger,” said the former Theranos manager, who asked not to be named. “Everyone who knows Elizabeth knows that she saw herself as a company, and I don’t think she can see the company going on without her.”

Holmes left Stanford at 19 to start Theranos. By the time the company collapsed in 2018, she had a six-figure salary and a multi-billion dollar stake in the blood testing startup.

However, an investigation by the Wall Street Journal found that the technology didn’t work as Holmes claimed it did. Now she faces a dozen fraud charges for falsely claiming that Theranos technology can perform dozens of blood tests on a drop or two of blood. She pleaded not guilty.

Despite the chaos in the final months of her reign, Holmes believed Theranos could still be saved.

Holmes achieved a partial victory this week when the judge ruled that defenders can refer to Silicon Valley’s hype culture to explain why Holmes exaggerated the technology behind Theranos.

No, night time mode does not assist

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No, night time mode does not assist

Person looking at their phone in bedPhoto: DimaBerlin (Shutterstock)

When it gets dark, you may notice your phone’s screen turn more orange to prepare you for sleep. Our body expects to see only blue light during the day, according to the theory. So if we block out blue light at night, we should relax and feel more tired when it’s time for bed.

It’s true that using your phone before bed is likely to interfere with your sleep, but can a change in color really reverse that effect? Not likely after new research that confirms what experts have been saying for years.

What we recently learned

In the new study, college students were assigned one of three conditions: inserting their iPhone in the hour before bed, using their iPhone with the night shift turned on, or using their iPhone without the night shift. There were no differences between the three groups in terms of sleep quality as measured by an activity tracker.

“Taken together, our study results in combination with the previous literature do not support blue light filters (such as night shift) as interventions to improve sleep, regardless of whether they are based on sleep characteristics (e.g. duration of sleep, latency of the onset of sleep, onset of melatonin or minutes) are measured while sleeping with quick eye movements, ”write the investigators.

College students are notoriously sleepless, however, and researchers wondered if the participants were perhaps so tired they could easily fall asleep no matter what they did on their cell phones. When they looked at the people who had more than the average amount of sleep – in other words, those who were less likely to be deprived of sleep – they found a difference in sleep quality between people who used their phones before Bedtime, and those who didn’t, but once again using Night Shift didn’t seem to make a difference.

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What we already knew

Night Shift (and its androids and computers equivalents) is based on science that made sense but wasn’t rigorously tested when it was first introduced in the real world. Here’s a Lifehacker piece from 2016For example, when these modes were just beginning to take hold and we found that while science backed the idea that blue light could interfere with sleep, we didn’t know if the orange hue of your display would actually fix the problem.

Today blue light has an even worse reputation, but the science that supports it hasn’t really emerged. Opticians and ophthalmologists keep trying to tell us The blue light from screens doesn’t have any serious health effects and they don’t recommend night mode as a panacea for smartphones that interfere with our sleep.

In short, use the night mode to relax in the evening American Academy of Ophthalmology saysHowever, you should still put your phone away for an hour or two before bed so it doesn’t interfere with your sleep.

Graphic new allegations emerge in Josh Duggar’s little one pornography case

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Graphic new allegations emerge in Josh Duggar’s little one pornography case

Faulkner said Josh was a registered member and his pregnant wife. Anna Duggarreceived reports of its online activity. However, Faulkner claimed that Josh’s activity was not monitored by the program because he was using a password-protected network.

At Wednesday’s hearing, a judge granted Josh bail on condition that he stayed with the Rebers, who are friends of the Duggar family and have agreed to be his third party administrators. In addition, he is monitored with a GPS anklet, he cannot access the internet and he can visit with his children while his wife monitors, among other things.

Josh pleaded not guilty on Friday, April 30th, of once receiving child pornography and once possessing child pornography.

At the time of his indictment, he was the US Chief Justice Erin L. Wiedemann said Josh would not be allowed to live with underage children if he was given bail.

His attorneys spoke out against the verdict in an appeal filed Tuesday, May 4th and submitted by E! News. His attorneys asked the judge to allow Josh’s bail release on “a combination of conditions”, adding, “Duggar is asking this court to allow him to return to his immediate family while this case is pending.”

Methods to inform if a web-based petition is value your time

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Methods to inform if a web-based petition is value your time

Protest sign: Photo: Halfpoint (Shutterstock)

Creating a petition to complain about an injustice is easy and it may be cathartic to sign one, but not all petitions have the ability to make change. Here are the factors that experts say will make the difference between petitions that make a difference and those that don’t.

Does the petition have a clear goal?

A petition is probably best thought of as a letter from a group of people to a specific entity asking that entity to do a specific thing. The idea is that the person or company receiving the petition reads it, notices the huge list of names below, and considers whether they should take any action other than what they had planned.

In order for the petition to achieve anything, it must actually have a goal. Make sure the petition is clear about what specific action it is, and make sure that goal makes sense in the context of the larger problem. For example, after Cecil the lion was killed by a hunter, Some petitions have asked the airlines to stop transporting endangered animals. This is a concrete change in policy related to hunting tourism, as opposed to the petitions asking the hunter to lose his dental license or other petitions that had no clear aim at all.

Is the petition for a person who can achieve the goal?

Change.org recommends that the petitioners identify a “decision maker” as the target of a petition. Naming a person means having an email address and the name of the person on the petition to better get their attention. When looking for the decision maker, the organizer has to find out who actually makes the relevant decisions. Sometimes the person you need to reach isn’t a well-known politician or CEO, but someone in a lesser-known job who still has the authority to make changes.

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Does the goal of the petition have any cause for concern?

Since the goal of a petition is to get the decision maker to change their mind, it helps to see who signed the petition. For example, the mayor of a city in Texas might not care what the people of Ohio have to say about local laws. And a for-profit company will care more about the opinions of its customers and prospects than about people who are completely outside of their target audience.

When a problem is big enough, it can be helpful for the decision maker to know that people from all over the country are interested. With many smaller problems, however, it is not important how many people sign a petition, but who they are.

There are many ways to make a difference

Even if a petition doesn’t achieve its stated goal – or if it doesn’t have a specific goal – it doesn’t always mean that the petition is a waste of time. Sometimes while collecting signatures, the petition organizer helps supporters of a cause to find each other. (This often means collecting the signers’ contact information, so make sure you land on a mailing list.)

A petition can also show that there is enough interest in a subject to be worthy of media coverage, and that the coverage can in turn be part of a campaign to put pressure on an individual or group. That way, a vague petition may not lead to immediate action, but it could be a sign that a larger movement is brewing.

However, there is more to a petition than what happens after it is signed. Sometimes there is a petition that can be read by those who sign it. It is more like a sharable article than a letter to an opposing unit. and sometimes signing and sharing a petition can be a person’s small step in taking action on an issue that is important to them.

Whether you choose to sign a petition with no clear purpose is up to you. However, if you have a specific, immediate change you want to make, look for petitions that have a clear goal and a workable way to achieve it.

The USA waived patent safety for Covid vaccines, citing the worldwide well being disaster

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The USA waived patent safety for Covid vaccines, citing the worldwide well being disaster

WASHINGTON – The Biden government announced on Wednesday that it supports the waiver of intellectual property protection for Covid-19 vaccines as countries struggle to manufacture the life-saving doses.

“This is a global health crisis, and the extraordinary circumstances of the COVID-19 pandemic call for extraordinary measures. The government firmly believes that intellectual property protection is needed, but in the service of ending this pandemic, the removal of that protection for COVID-19 is essential supports vaccines, “United States sales representative Katherine Tai wrote in a statement.

“With our vaccine supplies secure for the people of America, the government will continue to work – in collaboration with the private sector and all possible partners – to expand the manufacture and distribution of vaccines. It will also work to obtain the raw materials it needs increase.” produce these vaccines, “added the statement.

World Health Organization Director General Tedros Adhanom Ghebreyesus praised the US decision as a “monumental moment in the fight against Covid-19”, reflecting the White House’s “moral leadership” in the fight against the pandemic.

Shares of major pharmaceutical companies that made vaccines, including Moderna, BioNTech, and Pfizer, fell sharply after the potential was revealed Disclaimers broke first. Pfizer ended its trading day flat while Moderna lost 6.1%; Johnson & Johnson lost a modest 0.4%.

The Pharmaceutical Research and Manufacturers of America spoke out against the Biden government’s support for the waiver of IP protection. Members of the trading group include vaccine manufacturers such as AstraZeneca, Pfizer, and Johnson & Johnson.

“Amid a deadly pandemic, the Biden administration has taken an unprecedented move that will undermine our global response to the pandemic and threaten security,” said Stephen J. Ubi, group president and CEO. “This decision will create confusion between public and private partners, further weaken already tight supply chains and encourage the proliferation of counterfeit vaccines.”

World Trade Organization leaders reportedly this week urged member states to swiftly clarify the details of an agreement to temporarily relax the intellectual property rules behind coronavirus vaccines. The derogation proposed by South Africa and India could remove barriers to increasing vaccine production in developing countries.

An administrative official, aware of Tai’s decision, warned that the WTO’s discussions on derogations could take some time, and since the panel’s decisions are based on consensus, the consent of all 164 members is required.

The official, who spoke on condition of anonymity, added that Tai had held at least two dozen meetings and calls with various industry stakeholders, including major vaccine manufacturers. The person added that Tai is committed to amicable collaboration among global companies to remove supply chain bottlenecks.

White House President Joe Biden on Wednesday reiterated that the White House would support the World Trade Organization’s proposal to suspend intellectual property. “Yes, I’ll talk about that later today. Yes,” Biden said just before Tai’s statement was released.

The move by the Biden government comes because coronavirus infections have soared to their highest levels in countries that have struggled to source or distribute vaccines, contrasting with other nations such as the US, Canada and the UK

46-year-old Edith Arangoitia (who came to accompany her older mother) was born on February 16, 2021 by Dr. Galen Harnden in La Colaborativa in Chelsea, Massachusetts, was vaccinated with the Pfizer-BioNTech Covid-19 vaccine.

Joseph Precious | AFP | Getty Images

In the past few weeks, India has been grappling with a staggering surge in new coronavirus infections. Over the weekend, India reported 400,000 cases per day for a cumulative total of 20,665,148 cases. This comes from figures compiled by Johns Hopkins University. The spike may have been triggered by a highly contagious variant of Covid known as B.1.617, which was first identified in India.

The variant has since been identified in other countries, including the United States.

In April, Indian Prime Minister Narendra Modi discussed lifting patent protection for coronavirus vaccines with Biden. The relaxation would give governments faster and more affordable access to the life-saving doses.

Last week, the Biden government announced that it would immediately provide the raw materials needed to manufacture coronavirus vaccines in India.

Critics have argued that vaccine patents and other safeguards are not the central barrier to producing more vaccines for the nations that need them most. Some also suggest that such agreements could undermine firms’ incentives to innovate.

“This is a major misstep by the Biden administration that will do nothing to improve vaccine distribution and support China’s ability to use US innovation to achieve its vaccine diplomacy goals,” said Clete Willems, former attorney with the US office – Sales agent said the decision.

“A solution that is more in line with the government’s stated goals of improving US competitiveness and maintaining jobs in America would be to manufacture and export vaccines from the US,” said Willems, who served under both the Obama administration and the United States also worked under the Trump administration.

A Washington Post editorial this week said the goal of developing a “popular vaccine” to defeat Covid was “more a slogan than a solution.”

– CNBC’s Kevin Breuninger and Tom Franck reported from New York.

The best way to Robotically Label Your Instagram Tales

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The best way to Robotically Label Your Instagram Tales

You can now add a “closed caption sticker” to Instagram Stories that will automatically translate your audio into closed captions without the need for third-party apps. This is a helpful tool for developers and audiences as it makes videos with live subtitles more accessible for people with hearing impairments and for those who prefer to watch with the sound off.

Unlike the automated subtitles in live IGTV videos, the new subtitle stickers are more like intentional video elements than simple text at the bottom of the screen. However, you can also go for the simple subtitle look if that’s your preference. As with other Instagram stickers, you can change the position, color, size and font of the label and edit the text that is labeled. This is useful when the app hears a word wrong. You can also use the Pen tool to draw below or above the screen captions.

To start with, subtitle stickers only work for English and are therefore only provided to iOS and Android users in predominantly English-speaking countries. According to Instagram, the sticker will soon be able to be used in Instagram Reels videos as well, and could be incorporated into other types of Instagram video content in the future.

How to add caption stickers to Instagram Stories (and finally Reels)

Illustration for article titled How to Automatically Label Your Instagram StoriesImage: Instagram

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  1. Open the Instagram app and record a new story or reels video. You can also choose a video stored on your device to publish instead.
  2. While editing the video, select the sticker icon from the editing options above.
  3. Choose “Captions” from the list.
  4. Place the sticker where you want it to appear. A preview of the text is displayed while the video is playing.
  5. If necessary, tap a word to edit it and use the sticker editing options to change the label design and layout.
  6. When you’re done editing, publish the video. The subtitles will appear automatically when your video is played.

[TechCrunch]

The COVID-19 Small Enterprise Assist Program is operating out of cash

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The COVID-19 Small Enterprise Assist Program is operating out of cash

NEW YORK – The main government aid program for COVID-19 for small business is out of money.

The Small Business Administration announced Wednesday that the paycheck protection program was exhausted. As of Sunday, the PPP had issued nearly 10.8 million loans valued at more than $ 780 billion since April last year.

The program, which ran out of money twice and was reimbursed twice by Congress, was due to expire on May 31. It is not yet known whether lawmakers will approve another round of funding.

The SBA said in a statement that it will continue to fund approved applications. New applications made through community financial institutions, which are financial lenders serving underserved communities, would also be funded.

More than half of the loans and almost a third of the loan money were distributed that year. The average loan size was $ 46,000, less than half the average loan of $ 101,000 in 2020. This is a sign that smaller businesses that couldn’t get loans last year are now getting funding. Businesses were drawn to the loans because they promised forgiveness if the money was used on payroll and other essentials.

While the PPP helped save many businesses destroyed by the pandemic, the Biden government has estimated that more than 400,000 U.S. businesses have permanently closed due to the virus.

Small businesses have even more help available through SBA Economic Injury Disaster Loans, and restaurants with no more than 20 locations can apply for grants through the Restaurant Revitalization Fund, which accepted applications Monday. Aid is also available to theater and other entertainment company owners through the Shuttered Venues Operator Grants.

The PPP has been criticized because many very small businesses, including those owned by minorities, have struggled to get their applications accepted by banks. Many of these companies had to wait weeks or months for community banks, credit unions, and online lenders to join the SBA’s list of financial institutions.

“The program has always been fundamentally flawed because it was based on an unequal traditional banking system,” said John Arensmeyer, CEO of Small Business Majority, an advocacy group. Congress should consider more grants to help companies still struggling with the pandemic, he said.

Karen Kerrigan, president of the Small Business & Entrepreneur Council, said she “got a feel for PPP through conversations on Capitol Hill”. She said private sector investment and credit are needed to help small businesses recover and start new businesses.

The PPP has also been criticized for imposing restrictions on sole proprietorships without employees. For example, they couldn’t apply for loans until a week after the program started on April 4, 2020. Many also found it difficult to meet paperwork requirements for loans.

Keith Hall, advocacy president of the National Association for the Self-Employed, said all companies whose applications have been delayed due to restrictions should continue to receive their loans, even if it means Congress needs to allocate more funding to the PPP.

Joyce M. Rosenberg, The Associated Press

Drew Scott shares the most effective man’s want for Jonathan

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Drew Scott shares the most effective man’s want for Jonathan

Drew ScottThe wedding wish came true.

In a new YouTube video reflecting on his 2018 wedding to his current wife Linda PhanThe Property Brothers star spoke about it as did his identical twin brother Jonathan ScottThe best man’s speech inspired Drew to make a sweet wish for himself.

Jonathan said in his speech at the couple’s wedding reception in Italy: “Although Drew and I look very similar on the outside, we are two very different people on the inside. He’s the type who just introduces himself to everyone.” Am I glad he went up to this stranger at Fashion Week in 2010 and said hello? “

Drew watched the wedding speech on the new video and remembered how he felt when he heard his brother’s kind words.

“It still makes me constipated,” Drew explained. “I remember thinking when he cried during that speech that I just wanted to see him find someone to fall in love with, so I’m glad he did.”

Individuals who have been vaccinated with Covid could have higher safety towards variants

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Individuals who have been vaccinated with Covid could have higher safety towards variants

Dr. Anthony Fauci, director of the National Institute for Allergies and Infectious Diseases, speaks during a press conference at the White House in the James Brady Press Briefing Room of the White House on January 21, 2021 in Washington, DC.

Alex Wong | Getty Images

People who had Covid-19 and were later vaccinated may have more protection from highly contagious variants, said White House chief medical officer Dr. Anthony Fauci, on Wednesday.

Fauci cited a study published in late April that found that people with previous coronavirus infections had better immune responses to B.1.1.7 and B.1.351, first used in the UK and the South, after a dose of the Pfizer BioNTech vaccine identified variants of Africa compared to those that did not have Covid.

He cited an additional study published online that has not yet been peer-reviewed. It found that people with previous infections who were later fortified with two doses of an mRNA vaccine had “increased protection” against variants.

The studies provide more evidence of the benefits of vaccination, Fauci said.

“Vaccines are very effective,” Fauci said during a Covid briefing at the White House. “You are better than the response you get from a natural infection.”

His comments stem from the Biden government’s drive to partially vaccinate 70% of adults in the United States and 160 million adults fully by July 4th. This is a date the government hopes will mark a turning point in the pandemic.

Over the past few weeks, the pace of people getting their first doses of vaccine has slowed, despite U.S. health officials say they’re working to improve access to the shots and encourage more reluctant Americans to get vaccinated.

Earlier Wednesday, the Centers for Disease Control and Prevention released a new report forecasting Covid-19 cases to rise through May before falling sharply into July as vaccinations reduce infections.

Highly contagious variants, namely the highly contagious B.1.1.7 identified for the first time in Great Britain, remain a wild card, according to US health authorities. They urge Americans to get vaccinated and take safety measures against pandemics.

“We are seeing that our current vaccines protect against the pollutants circulating in the country. Put simply, the sooner more people are vaccinated, the sooner we will all get back to normal,” said CDC Director Dr. Rochelle Walensky during the press conference.

This is the way to snap commencement images that you simply really like

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This is the way to snap commencement images that you simply really like

Illustration for article titled How To Take Graduation Photos You Actually LikePhoto: Freedomz (Shutterstock)

Graduations are a big deal as they can only be photographed once in most contexts. Once your graduate has passed the stage to get their high degree, there is no way you can do anything because you missed the crucial moment.

No matter how awkward your loved ones look in their hats and clothes, you will want to capture the milestone to the fullest. Here are some tips for great graduation photos.

Increase your ISO and try to isolate your subject

Graduation ceremonies are usually sprawling affairs. Using a telephoto lens, the primary purpose of which is to take pictures of people far from the camera, is certainly the best option. This will help you wade through the crowd and focus the shot on your preferred subject unlike any other graduate you may not know.

In addition, telephoto lenses are good at blurring the background of an image so that your subject really shines. They’re also good for portrait photography, which is essentially what you want, albeit at a distance. How Notes on rental lensesThis type of lens is especially flattering for your subject.

This effect can also make facial features appear more proportional. Add to that the beautiful bokeh from taking photos with a long lens and you have a great tool for portrait photography.

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Another key if you are using a digital SLR camera – and especially if you are not an expert – is improving your ISO performance. The ISO refers to the sensitivity of your camera to light. When using a long lens or photographing a fast-moving subject, such as a portrait. For example, a sprinter or even someone walking across a stage, a higher ISO setting will help produce razor-sharp images.

If you’re shooting in daylight, a lower, but still somewhat high, ISO is recommended, but becomes even more important in low-light conditions, such as in a cave-like gym. Digital Photography School Details of some best practices:

Sure, when the light is bright, you can keep the ISO at 100 or 200 and get sharp, well-exposed images. But when the light starts to fall, you need to increase your ISO with confidence. This allows you to take bright and clear photos of 300mm, 400mm and more.

Another piece of advice, especially for laypeople who may not have fancy lenses, is to set the camera to automatic settings. If you do, then you can also try using an auto focus lens that allows you to sit back and just enjoy the process.

And of course you should (or not) consider the flash. Nikon recommends Only use it when you are near your drawer and indoors – two conditions that likely won’t apply to your graduation ceremony at the same time.

Unless you’re relatively close [read: in a classroom], don’t bother to use a flash. The flash won’t reach your subjects, so it won’t help with exposure and can drain your batteries.

Pointers to good pictures to take

Good photographers – even the amateurs – capture the subtle moments. So you need to strike a healthy balance between stealthy portraits of the day’s celebrations and staged photos.

One point that needs to be highlighted, at least thematically, is that this is a degree, which means that the equipment of such an event – the cap and gown, school, diploma, etc. – should be a focus. Basically, there are a number of different things you should try, all of which are in the broader portraiture category. Take portraits of the graduate with family, friends, and whoever you see fit. Try to include the school’s campus as recommended by Mimeo photos, what says:

Entrances and porticos are ideal. You won’t regret having that one picture in front of your school’s sign or mascot statue.

For taking real portraits, experts recommend using longer lenses for them too. For people who take photos with full-frame SLR cameras, this means “lenses with focal lengths between 70 mm and 200 mm”. according to DP Mag. As photographer and writer Jack Crosbie Lifehacker relates, longer lenses “make things look flatter, which is more flattering on people’s faces.” On the other hand, people make wider lenses look bigger and disproportionate to reality, on occasion.

Even then, think of all the big, solemn events that usually define a day, like throwing hats, crossing the stage, and partying with friends.

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